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Research Interests: My research interests encompass a diverse range of crucial biomedical areas. Firstly, I'm dedicated to understanding the role of apoptosis markers in breast cancer therapy, aiming to identify specific molecular pathways that can be targeted to improve treatment outcomes. Secondly, I delve into the complex interplay between oxidative stress and psoriasis, seeking to unravel how oxidative stress contributes to the pathogenesis of this chronic skin condition, potentially paving the way for innovative therapeutic interventions.Additionally, I am committed to exploring arginine metabolism-related biomarkers in chronic kidney disease (CKD) and end-stage renal disease (ESRD), with the aim of identifying novel diagnostic markers and therapeutic strategies to improve the lives of CKD and ESRD patients. Furthermore, my research delves into the discovery and validation of biomarkers for oral cancer, striving to advance early detection and treatment options for this debilitating disease. Lastly, I investigate the impact of MTHFR polymorphism in young individuals with coronary artery disease (CAD), aiming to unravel genetic factors contributing to CAD in this population and enhancing our understanding of personalized preventive care strategies. These research interests collectively underscore my dedication to advancing medical knowledge and improving healthcare outcomes across diverse clinical domains.

Publications 

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  • Academic Book Published

  1. Charushila Y. Kadam, Adinath N. Suryakar, R. V. Katkam Biomarkers for oral cancer - A serological study [ISBN: 978-3-    659-44970-3] LAP LAMBERT Academic Publishing, Germany.

  2. Charushila Y. Kadam. Practical Textbook of Biochemistry for MBBS-I (As per the revised competency based NMC curriculum including clinical case studies)-1st Edition. [Under submission for publication]

  • Laboratory Manual Published

  1. Charushila Y. Kadam (First and Corresponding author), Swati Agarwal.

      Laboratory Journal of Practical Biochemistry (Competency Based Practical Record Book),                  MBBS-Phase I, RKDF Medical College, Hospital and Research Centre, Bhopal, affiliated to SRK        University, Bhopal.

  • Book Chapter

  1. Kadam CY, Abhang SA. Apoptosis markers in breast cancer therapy.

      Book: Advances in Clinical Chemistry, 2016; 74:143-193 [ISBN: 978-0-12-804689-0]Burlington:           Academic Press, 2016, Elsevier Inc.

       [Figure from our chapter featured on the Cover of a book]

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  • Research Papers:

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  1. Gulajkar SR, Shivkar RR, Panchbudhe SA, Kadam CY. EQAS as a tool for evaluating laboratory performance in tertiary care hospital. Medical Laboratory Journal 10/2023.

  2. Panchbudhe S, Shaikh S, Swami H, Kadam CY, Padalkar R, Shivkar R, Gulavani G, Gulajkar S, Gawade S, Mujawar F. Efficacy of Google Form- based MCQ tests for formative assessment in Medical Biochemistry education. Journal of Education and Health Promotion, 2023. 

  3. Abhang SA, Narawade S, Kadam CY. Differential status of serum arginine, arginase and nitric oxide in patients with chronic kidney disease and advanced stage kidney disease undergoing hemodialysis. Biomedical and Pharmacology Journal, 2023, 17 (1). 

  4. Shivkar RR, Gawade GC, Padwal MK, Diwan AG, Mahajan SA, Kadam CY. Association of MTHFR C677T and A1298C polymorphisms with serum homocysteine, folate and vitamin B12 among patients with young coronary artery disease. Indian J Clin Biochem, 2021; 1-8.

  5. Kadam CY, Abhang SA. Effect of chemotherapy on serum nitric oxide levels in advanced stage breast cancer patients. Int J Res Med Sci, 2020; 8(1):189-193.

  6. Kadam CY, Abhang SA. Alterations in serum antioxidant profile in patients with metastatic breast cancer undergoing chemotherapy-An observational study. Sch J App Med Sci,2019; 7(12):4162-67.

  7. Kadam CY, Abhang SA. Serum levels of soluble Fas ligand, granzyme B and cytochrome c during adjuvant chemotherapy of breast cancer. Clinica Chimica Acta, 2015; 438: 98-102.

  8. CY Charushila, Abhang SA. NO/Cyt c ratio as a possible marker of efficacy of adjuvant chemotherapy in breast cancer. European Journal of Cancer, 2015; 51(Supplement 2), e11.

  9. Kadam CY, Abhang SA. Correlation of serum levels of reduced glutathione and glutathione-dependent enzymes with cytochrome c after 1st cycle of adjuvant chemotherapy in breast cancer. Research Journal of Recent Sciences, 2015; 4(2): 1-6.

  10. Kadam CY, Abhang SA. Evaluation of serum antioxidants during adjuvant chemotherapy of breast cancer- A prospective observational study. Biochemistry and Analytical Biochemistry, 2015; 4(2): 1000171.

  11. Kadam CY, Abhang SA. Evaluation of serum levels of reduced glutathione, glutathione-s-transferase and nitric oxide in breast cancer patients undergoing adjuvant chemotherapy. International Journal of Current Research and Review, 2013; 5(13): 51-57.

  12. Kadam CY, Katkam RV, Suryakar AN, Kumbar KM, Kadam DP. Biochemical markers in oral cancer. Biomedical Research, 2011; 22(1):76-80.

  13. Kadam DP, Suryakar AN, Ankush RD, Kadam CY, Deshpande KH. Role of oxidative stress in various stages of psoriasis. Indian Journal of Clinical Biochemistry, 2010:25(4):388-392.

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